Questions asked

How do you do fake namespaces in JavaScript

var com  { myNamespace:  member: "value" } };

What's the best way to do inheritance?

Use Prototypal inheritance.

How do you debug and test, profile JavaScript

YUI Profiler

FireBug

PageSpeed

YSlow

YUITest

JSpec

Shoulda.js

QUnit

How do you organize JavaScript files

Client side

     package managers

     YUI3 use()

Server Side

     Bundler

What is the Reactive Framework for JavaScript? (RxJS)

Read Matthew Podwysockis blog posts. He does an excellent job of covering what they are and how you use them.